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Genetic Toxicology

The Genetic Toxicology Department at SafePharm has a wealth of experience in the performance and interpretation of standard genotoxicity tests and can provide advice on the most cost-effective and efficient means of determining the genotoxic potential of a test material.

The department has 30 staff members and, therefore, a large capacity for routine studies, which means that we offer competitive prices and rapid turnaround times.

SafePharm has unrivalled experience in Japanese submissions under the METI Chemical Substance Control Law and the MOL Industrial safety and Health Law. Our agents in Japan, Media Services-Techno Support, ensure that we are provided with the latest information on Japanese regulatory affairs.

We offer a full range of testing, including (but not limited to):

  • Ames Test
  • Chromosome Aberration (in vitro)
  • Mouse Lymphoma (in vitro)
  • Micronucleus (in vivo)
  • Unscheduled DNA Synthesis (in vivo)
  • Chinese Hamster Ovary HPRT Assay (in vitro)
  • Comet Assay (in a range of tissues including liver, bone marrow, stomach, kidney etc)


Regulatory and Screening Protocols
 

Whether you require data to meet a specific regulatory requirement or screening data for health and safety purposes, we can recommend the most appropriate protocol design. In most cases available Standard Test Methods will fulfil our sponsors needs but custom protocols can be prepared as necessary.

 

 

 

 

 

 

 
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